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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MKNK1
All Species:
16.06
Human Site:
T254
Identified Species:
32.12
UniProt:
Q9BUB5
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BUB5
NP_001129025.1
465
51342
T254
P
I
T
T
P
E
L
T
T
P
C
G
S
A
E
Chimpanzee
Pan troglodytes
XP_001162271
453
49967
T242
P
I
T
T
P
E
L
T
T
P
C
G
S
A
E
Rhesus Macaque
Macaca mulatta
XP_001098645
414
46209
W232
Y
D
K
R
C
D
L
W
S
L
G
V
V
L
Y
Dog
Lupus familis
XP_539626
415
46182
S233
D
K
R
C
D
L
W
S
L
G
V
V
L
Y
I
Cat
Felis silvestris
Mouse
Mus musculus
O08605
427
47896
D242
T
F
Y
D
K
R
C
D
L
W
S
L
G
V
V
Rat
Rattus norvegicus
Q4G050
413
46195
D230
T
F
Y
D
K
R
C
D
L
W
S
L
G
V
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001235171
508
56331
T296
P
I
T
T
P
E
L
T
T
P
C
G
S
A
E
Frog
Xenopus laevis
Q9YGW0
418
46898
V236
C
D
L
W
S
L
G
V
I
L
Y
I
M
L
S
Zebra Danio
Brachydanio rerio
NP_001108211
459
51123
T260
P
I
T
T
P
E
L
T
T
P
C
G
S
A
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651986
1142
128445
S439
H
Q
S
A
R
E
I
S
Q
F
A
E
S
A
M
Honey Bee
Apis mellifera
XP_395927
516
58135
G281
S
D
C
G
W
E
R
G
E
N
C
Q
A
C
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_779905
511
56921
Y320
W
S
L
G
V
I
L
Y
I
L
L
C
G
H
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.7
87.9
82.8
N.A.
85.3
82.3
N.A.
N.A.
51.5
72
68.3
N.A.
20.3
46.1
N.A.
37.7
Protein Similarity:
100
96.7
88.1
85.8
N.A.
88.5
85.3
N.A.
N.A.
63.3
79.7
76.7
N.A.
28.2
63.1
N.A.
52.4
P-Site Identity:
100
100
6.6
0
N.A.
0
0
N.A.
N.A.
100
0
100
N.A.
20
13.3
N.A.
6.6
P-Site Similarity:
100
100
20
6.6
N.A.
0
0
N.A.
N.A.
100
0
100
N.A.
40
26.6
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
0
0
0
0
0
0
9
0
9
42
0
% A
% Cys:
9
0
9
9
9
0
17
0
0
0
42
9
0
9
0
% C
% Asp:
9
25
0
17
9
9
0
17
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
50
0
0
9
0
0
9
0
0
34
% E
% Phe:
0
17
0
0
0
0
0
0
0
9
0
0
0
0
0
% F
% Gly:
0
0
0
17
0
0
9
9
0
9
9
34
25
0
0
% G
% His:
9
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% H
% Ile:
0
34
0
0
0
9
9
0
17
0
0
9
0
0
9
% I
% Lys:
0
9
9
0
17
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
17
0
0
17
50
0
25
25
9
17
9
17
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
9
% M
% Asn:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% N
% Pro:
34
0
0
0
34
0
0
0
0
34
0
0
0
0
9
% P
% Gln:
0
9
0
0
0
0
0
0
9
0
0
9
0
0
9
% Q
% Arg:
0
0
9
9
9
17
9
0
0
0
0
0
0
0
0
% R
% Ser:
9
9
9
0
9
0
0
17
9
0
17
0
42
0
9
% S
% Thr:
17
0
34
34
0
0
0
34
34
0
0
0
0
0
0
% T
% Val:
0
0
0
0
9
0
0
9
0
0
9
17
9
17
17
% V
% Trp:
9
0
0
9
9
0
9
9
0
17
0
0
0
0
0
% W
% Tyr:
9
0
17
0
0
0
0
9
0
0
9
0
0
9
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _